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Vitamin C Beneficial in Heart Disease

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Vitamin C Beneficial In Heart Disease

From: Duke and the Doctor

Date: Mon Jun 3, 2002 9:17 am

Subject: Vitamin C Beneficial In Heart Disease

Vitamin C treatment has a possible role in benefiting patients with coronary heart disease by countering the adverse effects of the high- fat meal. The postprandial serum triglyceride concentration is raised after a high-fat meal and this postprandial state is critical in atherogenesis, inducing endothelial dysfunction through an oxidative stress mechanism. These were the findings of a study that included 74 patients with coronary heart disease and 50 people without the disease but who had risk factors. These two groups were split into subgroups: those who received 2g of vitamin C and those who did not after eating high-fat meal. The study was conducted by Dr. Ling Liu, Department of Cardiology, Hunan University, Hunan, People’s Republic of China, and co-workers. They found that postprandial serum triglyceride concentration increased significantly at two to five hours after the high-fat meal in all groups. The fasting flow-mediated dilatation and nitroglycerin-induced dilatation of patients with coronary heart disease were impaired compared with those without disease. Although the postprandial flow-mediated dilatation was significantly aggravated in people not taking vitamin C (both with and without heart disease), this parameter in patients and subjects taking vitamin C showed no significant change.

By Robert Short

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